Classes in Wasteland 3 are character role descriptions that are determined by the highest skill (or the first skill to get there, when there are several skills on the same level). There is no actual gameplay effect, except that the associated skill needs to be given priority in order to keep the class title.
| Class | Skill(s) |
| Brawler | Brawling |
| Combat Medic | First Aid |
| Commander | Leadership |
| Enforcer | Melee Combat |
| Explosive Expert | Explosives |
| Hacker | Nerd Stuff |
| Heavy Gunner | Big Guns |
| Infiltrator | Sneaky Shit |
| Inventor | Weird Science |
| Locksmith | Lockpicking |
| Mechanic | Mechanics |
| Modder | Armor Modding or Weapon Modding |
| Negotiator | Kiss Ass |
| Shepherd | Animal Whisperer |
| Survivalist | Survival |
| Sniper | Sniper Rifles |
| Thug | Hard Ass |
| Toaster Expert | Toaster Repair |
| Trader | Barter |
| Trooper | Automatic Weapons or Small Arms |
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